Egypt deplored the "targeting of defenceless civilians" and labelled it part of "a systematic policy aimed at widening the scope of death and destruction in the Gaza Strip to make it uninhabitable".
Jordan also expressed its condemnation, accusing Israel of committing "ongoing war crimes".
Kuwait charged the attack exposed Israel's "blatant war crimes and unprecedented genocide to the whole world".
And Qatar condemned the Israeli bombing as a "dangerous violation of international law".
Saudi Minister of Foreign Affairs, Prince Faisal bin Farhan bin Abdullah, stressed that “it is absolutely necessary that Israel accepts that it cannot exist without the existence of a Palestinian State.”